The "HEMIBIO" project (2011-2015)

Hepatic Microfluidic Bioreactor

 

Project coordinator : Prof. Catherine Verfaillie, KULeuven

Co-promotors for VUB

Prof. Leo van Grunsven - Liver Cell Biology -VUB
Prof. Vera Rogiers - Toxicology - VUB

Funding : EU-FP7-HEALTH

In HeMiBio, we propose to generate a liver-simulating device mimicking the complex structure and function of the human liver. The device will reproduce the heterotypic interactions between the parenchymal (hepatocytes) and non-parenchymal (hepatic stellate cells (HSC), hepatic sinusoidal endothelial cells (HSEC), and hepatic Kupffer cells) cells of the liver for over 1 month in vitro in a high-throughput format. Such a Hepatic Microfluidic Bioreactor could then serve to test the effects of chronic exposure to chemicals, including cosmetic ingredients
Back to top

©2004-2014• LIVR • Vrije Universiteit Brussel • Faculteit Geneeskunde & Farmacie • Laarbeeklaan 103 • 1090 Jette • Tel.: 02/477.44.09• jmlazou@vub.ac.be